Full Prescribing Information for BICILLIN® L-A
Indications and usage
Intramuscular penicillin G benzathine is indicated in the treatment of infections due to penicillin-G-sensitive microorganisms that are susceptible to the low and very prolonged serum levels common to this particular dosage form. Therapy should be guided by bacteriological studies (including sensitivity tests) and by clinical response.2
The following infections will usually respond to adequate dosage of intramuscular penicillin G benzathine:2
- Mild-to-moderate infections of the upper respiratory tract due to susceptible streptococci
- Venereal infections—syphilis, yaws, bejel, and pinta
- Medical conditions in which penicillin G benzathine therapy is indicated as prophylaxis:
- Rheumatic fever and/or chorea—prophylaxis with penicillin G benzathine has proven effective in preventing recurrence of these conditions. It has also been used as follow-up prophylactic therapy for rheumatic heart disease and acute glomerulonephritis.
Important notes
Bicillin® L-A is contraindicated in individuals with a previous hypersensitivity reaction to any of the penicillins.2 Use with caution in individuals with histories of significant allergies and/or asthma.2 Give only by deep intramuscular injection.2 Do not inject by any other route, such as intra-arterial or intravenous.2 Do not inject into or near nerves or blood vessels, since such injection might produce neurovascular or other damage.2
