BICILLIN® L-A for Syphilis
Bactericidal action against Treponema pallidum—to heal lesions and prevent sexual transmission2,6
In 2006, the Centers for Disease Control and Prevention (CDC) published the updated sexually transmitted diseases treatment guidelines. In this document, the CDC identifies penicillin G benzathine as a preferred drug for treatment of all stages of syphilis: primary, secondary, latent, and tertiary (with the exception of neurosyphilis and syphilitic eye disease).7
BICILLIN® L-A is the only formulation of intramuscular penicillin G benzathine that is FDA-approved for the treatment of syphilis. 10,12
Dosage and administration for BICILLIN® L-A
- Treponema pallidum, the bacterium that causes syphilis, is extremely susceptible to BICILLIN® L-A. BICILLIN® L-A exerts strong bactericidal action during the period when this bacterium is actively multiplying.2
- Physicians have used parenteral penicillin G for more than 50 years to effectively treat and to prevent sexual transmission of syphilis infection. 7
- A history of previous hypersensitivity reaction to any of the penicillins is a contraindication to the use of BICILLIN® L-A.2
Relevant links 
View a summary of the CDC treatment guidelines for sexually transmitted diseases, 2006.
View instructions on BICILLIN® L-A dosage and administration.
Note: BICILLIN® L-A is indicated for syphilis. BICILLIN® C-R is not.2,3 Learn about BICILLIN® C-R (penicillin G benzathine and penicillin G procaine injectable suspension).
